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A high-throughput, low-cost assay for DNA replication stress
When the base analogues EdU and BrdU are pulsed into S-phase cells, they are incorporated into newly copied DNA and form a "footprint" of...
Aug 20
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The first map of replication fork movement across extrachromosomal DNA
Together with Julian Sale's Lab at the MRC Laboratory of Molecular Biology, we published a paper entitled " ecDNA replication is...
Aug 12
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Our paper was featured in Nature Communications Editors' Highlights on genetics, genomics and epigenetics
We are delighted that our recent paper was selected by the editors of Nature Communications to feature in their Editors' Highlights on...
Jun 11
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A mathematical model for the regulation of replication timing in budding yeast
In our model for whole-genome replication in budding yeast, potential start sights of DNA replication (red) compete to associate with a...
Jun 11
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A new algorithm to identify difficult-to-replicate regions of the human genome
Our mathematical model creates a prediction of when each position of the human genome is replicated (red curve). Comparing the model's...
May 22
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Comparison of the DNA replication dynamics between two very different malaria parasites
Together with our longstanding collaborator Catherine Merrick's lab, we've published a paper in Nucleic Acids Research entitled "DNA...
Feb 24
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Nisha's paper published in Computers & Chemical Engineering
Our postdoc Nisha Gangadharan has published a paper in Computers & Chemical Engineering titled "Online data condensation for digitalised...
Sep 15, 2023
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New Publication: Mathematical modelling of 2D Notch-Delta signalling
Our postdoc Francisco Berkemeier has just published a new paper in Mathematical Biosciences on the dynamics of 2D Notch-Delta signalling...
May 23, 2023
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